Mirogabalin Impurity 3 CAS 1246542-68-6 (free base)
| CAS No. | 1246542-68-6 (free base) |
| Molecular Formula | C16H27NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Mirogabalin Impurity 3 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Mirogabalin Impurity 3 (CAS 1246542-68-6 (free base), C16H27NO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mirogabalin Impurity 3 (C16H27NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H27NO2 HCl |
| Molecular Weight | 301.86 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Mirogabalin Standards
- Mirogabalin (CAS 1138245-13-2)
- Mirogabalin Impurity N85 (CAS 1138245-15-4)
- Mirogabalin Impurity 61 Formate Salt (CAS 1138245-15-4 (free base))
- Mirogabalin Impurity (CAS 1138245-20-1)
- Mirogabalin besylate (CAS 1138245-21-2)
- Mirogabalin Impurity 16 (CAS 1138245-48-3)
- Mirogabalin Impurity 18 (CAS 1138245-49-4)
- Mirogabalin Impurity 42 (CAS 1138245-50-7)
Recommended Standards
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Folic Acid EP Impurity E Sulfate (CAS CATO-C4X-139541)
- Pemetrexed Impurity 28 (CAS CATO-C4X-172628)
- Methyl 1,6-dimethyl-4-oxo-1,4-dihydropyridine-3-carboxylate (CAS 1820620-45-8)
- 3-(4-Chloro-3-(trifluoromethyl)phenyl)-5,5-dimethylimidazolidine-2,4-dione (CAS 70842-05-6)
- Pyrantel EP Impurity B HCl (CAS 1449108-90-0)
- Tetrabromobisphenol A Diglycidyl Ether (CAS 3072-84-2)
- 5-(Piperidin-4-yl)-1,2-oxazol-3-ol hydrobromide (CAS 1215466-71-9)
- 3-(Difluoromethyl)-5-((4-methoxy-2-nitrophenyl)thio)-4H-1,2,4-triazole (CAS 1706450-48-7)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com